The prevalence of rheumatic heart disease in Samoa is among the highest in the world, affecting up to 8 percent of the youth population. The Rheumatic Relief Internship program is an integrated clinical, public health, and research experience that seeks to reduce the suffering associated with this potentially fatal disease. Students will shadow medical professionals, including board certified cardiologists, in diagnosing this largely silent disease in Samoan youth five–fifteen years old. They will provide public health promotion programs in primary schools to decrease the incidence of this disease. Finally, students will participate in genetic studies that help to better understand the genetic risks that may contribute to the high rates of rheumatic heart disease throughout Polynesia. In all aspects of this program, participants will work closely with indigenous medical and educational professionals to promote a lasting change in Samoa that will result in a sustainable improvement in medical care.